Her next romantic comedies, Alex and Emma (2003), in which she played a stubborn stenographer, and Raising Helen (2004), taking on the role of a young woman who becomes the guardian of her deceased sister's children, were released to varying degrees of success. In 2005, Hudson starred in the supernatural thriller The Skeleton Key, as a young hospice nurse who acquires a job at a New Orleans plantation home, and becomes entangled in a supernatural mystery involving the house. In its review, The Washington Post, describing her, wrote: "Hudson, who dials back her native, Goldie-given charm here to give Caroline a no-nonsense brusqueness, manages to convincingly convey a fearless bullheadedness rather than less sympathetic naivete". The film was a box office hit, grossing over US$91. 9 million worldwide ($47. 9 million in North America). Her next film, the comedy You, Me and Dupree, in which she appeared with Owen Wilson and Matt Dillon as one half of a couple who allows an unemployed friend to move in, grossed US$21. 5 million on its opening weekend of July 14, 2006. It eventually made US$130. 4 million worldwide.